MATHMOD 2022 Discussion Contributions

Modeling Whole Heart Muscle Fibers in Cardiac Computational Models

ARGESIM Report 17 (ISBN 978-3-901608-95-7), p 75-76, DOI: 10.11128/arep.17.a17181

Abstract

A crucial issue in simulating the heart function is accounting and modeling the arrangement of myocardial fibers that characterizes the cardiac tissue. Aggregations of myofibers, namely the results of cardiomyocytes orientation, plays a key role in the electric signal propagation and in the myocardial contraction. This motivates the need to accurately include muscular fibers in cardiac computational models (CCM). Rule-Based-Methods (RBMs), which provide a surrogate of myocardial fibers field, are one of the most used strategy to prescribe fiber orientation in CCM. In this work, we present a Laplace-Dirichlet-Rule-Based-Method (LDRBM), a particular class of RBMs, for generating myocardial whole heart fibers directly on full heart computational geometries. The methodology is straightforward and can be easily applied to any four-chambers models. The heart LDRBM includes a detailed myocardial fiber architecture and is able to quantitatively reproduce almost all the features of the different four-chambers, particularly those of the right ventricle and the atrial bundles.